The lipocalin protein family: structure and function
نویسندگان
چکیده
منابع مشابه
The lipocalin protein family: structure and function.
The lipocalin protein family is a large group of small extracellular proteins. The family demonstrates great diversity at the sequence level; however, most lipocalins share three characteristic conserved sequence motifs, the kernel lipocalins, while a group of more divergent family members, the outlier lipocalins, share only one. Belying this sequence dissimilarity, lipocalin crystal structures...
متن کاملLipocalin structure and function.
The lipocalins are a family of proteins the common function of which is to bind small hydrophobic substances. Although the amino-acid sequence similarity among the members of the family is low, there are two regions where the sequences are conserved. These are GXW and TDY (where X is usually acidic) [ 11. X-ray crystallography of several members of the family revealed that they exhibit a high d...
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The Lipocalins are an ancient protein family whose expression is currently confirmed in bacteria, protoctists, plants, arthropods, and chordates. The evolution of this protein family has been assessed previously using amino acid sequence phylogenies. In this report we use an independent set of characters derived from the gene structure (exon-intron arrangement) to infer a new lipocalin phylogen...
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The lipocalins are a family of extracellular proteins that bind and transport small hydrophobic molecules. They are found in eubacteria and a great variety of eukaryotic cells, in which they play diverse physiological roles. We report here the detection of two new eukaryotic lipocalins and a phylogenetic analysis of 113 lipocalin family members performed with maximum-likelihood and parsimony me...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1996
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj3180001